MOX1, also known as MEOX1, is a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes that is first expressed during gastrulation in the early mesoderm and later in presomitic mesoderm, early somites, dermomyotome and sclerotome. Both MOX1 and the related protein MOX2 are required for proper gene expression in all somitic compartments. MOX1 is an upstream regulator of the transcription factors Bapx1, Tbx18, and Uncx and is thus part of a regulatory circuit that functions in the maintenance of rostrocaudal sclerotome polarity and axial skeleton formation.
应用类型
ELISA,IF Microscopy,Western Blot,
免疫原
Anti-MOX1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the internal region of human MOX1.
来源宿主
Rabbit
反应性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建议
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.