Cyclophilin A is a multifunctional protein that is upregulated in a variety of inflammatory conditions, such as rheumatoid arthritis, autoimmune disease, and cancer. It has been classified as an immunophilin and has a variety of intracellular functions, including intracellular signaling, protein trafficking, and the regulation of other proteins activity. Besides its intracellular functions, Cyclophilin A is a secreted molecule that has a physiological and pathological role in cardiovascular diseases, making it a potential biomarker and mediator in cardiovascular diseases, such as vascular stenosis, atherosclerosis, and abdominal aortic aneurysms.
序列
重组人亲环蛋白 A 蛋白产品,又称Peptidylprolyl isomerase A, PPIA, CYPA, CYPH.其对应NCBI基因号为5478,对应Accession号为P62937.
来源宿主
提供的【Cyclophilin A 】重组人亲环蛋白 A 产品的来源为大肠杆菌重组表达.
溶解建议
重组人亲环蛋白 A 产品为液体即用型,其溶液组成为:1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 20 mM NaCl, 0.5 mM DTT, 10% glycerol.
保存建议
在您收到艾美捷发出的【Cyclophilin A 】重组人亲环蛋白 A 产品后,建议将其置于-80°C保存.