Aldo-keto reductase family 1 member C3 in humans is encoded by the AKR1C3 gene. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation.
序列
重组人AKR1C3蛋白产品,又称Aldo-keto reductase family 1, member C 3, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5.其对应NCBI基因号为8644,对应Accession号为P42330.
来源宿主
提供的【AKR1C3】重组人AKR1C3产品的来源为大肠杆菌重组表达.
溶解建议
重组人AKR1C3产品为液体即用型,其溶液组成为:1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.