AKR1B10 is a monomeric protein that efficiently catalyzes the reduction of aromatic and aliphatic aldehydes and ketones. AKR1B10 is ubiquitously expressed in many human tissues but is highly expressed in small intestine, colon and adrenal gland. This protein is pathogenically involved in diabetic complications. It has been reported that AKR1B10 is overexpressed in human tumors, such as liver, breast, and lung cancer, and may play a critical role in the development and progression of cancer.
序列
重组人AKR1B10蛋白产品,又称Aldo-keto reductase family 1, member B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HIS.其对应NCBI基因号为57016,对应Accession号为O60218.
来源宿主
提供的【AKR1B10】重组人AKR1B10产品的来源为大肠杆菌重组表达.
溶解建议
重组人AKR1B10产品为液体即用型,其溶液组成为:1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.