Glutathione S-transferase Mu 2 (GSTM2) belongs to the Glutathione S-Transferase (GST) family of proteins. There are 8 families of GST proteins: alpha, kappa, mu, omega, pi, sigma, theta and zeta, each of which is composed of proteins that have various functions throughout the cell. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are structured in a gene cluster on chromosome 1p13.3 and are proven to be highly polymorphic. These genetic variants can change an individual's susceptibility to carcinogens and toxins as well as have an effect on the toxicity and efficacy of several drugs.
序列
重组人GSTM 2蛋白产品,又称Glutathione S-transferase Mu 2, GST4, GSTM, GSTM2-2, GTHMUS.其对应NCBI基因号为2946,对应Accession号为P28161.
来源宿主
提供的【GSTM 2】重组人GSTM 2产品的来源为大肠杆菌重组表达.
溶解建议
重组人GSTM 2产品为液体即用型,其溶液组成为:0.5 mg/ml solution in 20 mM Tris HCl (pH 8.0) containing 10% glycerol, 0.1 M NaCl and 1 mM DTT.