CBS Antibody (NT) (CBS; Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase)
供应商
Biovision
产品货号
6729-100
产品报价
¥已停产
产品说明书
购买方式
银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868.
产品新闻
背景资料
Strongly expressed in human liver and pancreas,with weaker expression in heart and brain,the cytoplasmic protein cystathionine b-synthase (CBS) operates in the first step of homocysteine transulfuration. CBS,which belongs to the cysteine synthase/cystathionine b-synthase family of proteins,catalyzes the formation of cystathionine from the thrombogenic amino acid homocysteine using pyridoxal phosphate cofactor. Allosteric activation by adenosyl-methionine regulates CBS activity. Deficiencies in CBS are associated with homocystinuria,a recessively inherited error in sulfur amino acid metabolism that affects many organs and tissues. Symptoms of homocytinuria include arteriosclerosis,thrombosis,dislocated optic lenses,mental retardation and skeletal abnormalities.
应用类型
Western blot: ~1:1000, IHC: ~1:50–1:100, IF: ~1:10–1:50, FACS: ~1:10-1:50.
免疫原
This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human CBS.