C-Myc抗体-C-Myc Antibody （MYC； BHLHE39； Myc proto-oncogene protein； Class E basic helix-loop-helix protein 39； Proto-oncogene c-Myc； Transcription factor p64）代理/参数/厂家-二抗-开云·官方站线上登录平台入口

PRODUCT CENTER

二抗

开云·官方站线上登录平台入口_开云(中国)

当前位置：开云·官方站线上登录平台入口 > 开云·官方站线上登录平台入口_开云(中国) > 免疫学产品 > 二抗

英文名字: C-Myc Antibody （MYC； BHLHE39； Myc proto-oncogene protein； Class E basic helix-loop-helix protein 39； Proto-oncogene c-Myc； Transcription factor p64）

背景资料: c-Myc-，N-Myc- and L-Myc-encoded proteins function in cell proliferation，differentiation and neoplastic disease. Myc proteins are nuclear proteins with relatively short half-lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung，breast and colon carcinomas，while the N-Myc gene has been found amplified in neuroblastoma. The L-Myc gene has been reported to be amplified and expressed at high level in human small cell lung carcinomas. The presence of three sequence motifs in the c-Myc COOH terminus，including the leucine zipper，the helix-loop-helix and a basic region provided initial evidence for a sequence-specific binding function. A basic region helix-loop-helix leucine zipper motif （bHLH-Zip） protein designated Max，specifically associates with c-Myc，N-Myc and L-Myc proteins. The Myc-Max complex binds to DNA in a sequence-specific manner under conditions where neither Max nor Myc exhibit appreciable binding. Max can also form heterodimers with at least two additional bHLH-Zip proteins，Mad and Mxi1，and Mad-Max dimers have been shown to repress transcription through interaction with mSin3.

免疫原: This MYC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from human MYC.

保存建议: 提供的C-Myc抗体产品为无色溶液形式，含有100 ul抗体.该产品浓度为与批次相关，溶解于in 包含有0.09% （W/V）叠氮化钠的PBS缓冲液中.请在收到该C-Myc抗体产品后，将其置于-20 °C冷冻保存，建议分装使用以避免反复冻融.

其他: BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.