Cyclin E1抗体-Cyclin E1 Antibody [CCNE1, Cyclin Es, Cyclin Et, G1/S-specific cyclin-E1]代理/参数/厂家-二抗-开云·官方站线上登录平台入口

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二抗

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英文名字: Cyclin E1 Antibody [CCNE1, Cyclin Es, Cyclin Et, G1/S-specific cyclin-E1]

背景资料: Cyclin E1 is a regulatory subunit of the CDK2 kinase. It is central for the regulation of the G1/S transition and its abundance is tightly regulated throughout the cell cycle via ubiquitination. Cyclin E has been the subject of intense study in relation to tumorigenesis and cancer management and prognosis. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue，suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

免疫原: This Cyclin E1 antibody is generated from KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Cyclin E1. The exact sequence is proprietary.

保存建议: 提供的Cyclin E1抗体为无色溶液形式，产品浓度为1 mg/ml，溶解于包含有100 mM glycine与海藻糖的50 mM Tris缓冲液（pH 7.0）.请在收到该Cyclin E1抗体产品后，将其置于-20 °C冷冻保存，建议分装使用以避免反复冻融.

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