Meclofenamate, 2-[(2,6-dichloro-3-methylphenyl)amino]-benzoic acid, monosodium salt
供应商
Cayman
产品货号
70550-25
产品报价
¥2940/25 g
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产品新闻
背景资料
Meclofenamate is a time-dependent, non-specific competitive inhibitor of COX-1 and -2. The IC50 values for inhibition of human recombinant COX-1 and -2 are 1.5 and 9.7 uM, respectively for instantaneous inhibition. However, the IC50 is much lower if pre-incubated with the enzyme.
产品描述
Meclofenamate is a time-dependent, non-specific competitive inhibitor of COX-1 and -2. The IC50 values for inhibition of human recombinant COX-1 and -2 are 1.5 and 9.7 uM, respectively for instantaneous inhibition. However, the IC50 is much lower if pre-incubated with the enzyme.{1791}