AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain. Recombinant human soluble AITRL is a 14.4 kDa protein, containing 127 amino acid residues corresponding to the extracellular domain of AITRL.
序列
重组人AITRL蛋白产品,又称Activation-induced TNFR member Ligand, TNFSF18, GITRL, TL-6.其对应NCBI基因号为8995,对应Accession号为Q9UNG2.
来源宿主
提供的【AITRL】重组人AITRL产品的来源为大肠杆菌重组表达.
溶解建议
重组人AITRL产品请按照说明书建议进行溶解操作:Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.