中文名称

【PKCbII】PKCβ2蛋白，有活性的（5 ug）

英文名字

PKC BetaII, Active

供应商

Biovision

产品货号

7704-5

产品报价

￥已停产

产品说明书

购买方式

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产品新闻

背景资料

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Greenham determined the genomic structure of the PRKCβ gene, which consists of 18 exons spanning 375 kb (1). PRKCβ has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Leitges found that the 2 isoforms, PRKCβ1 and PRKCβ2, play an important role in B-cell activation and may be functionally linked to Bruton tyrosine kinase in antigen receptor-mediated signal transduction (2). Su proposed that PRKCβ inhibitors and inhibitors of other PRKC isoforms may be effective in treating disorders characterized by dysregulated NFKB survival signaling (3). Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress (4).

序列

PKC β2蛋白,有活性的蛋白产品，又称PKC, Protein kinase C beta II.其对应NCBI基因号为10000，NCBI基因别称为AKT3源，对应Accession号为NP_005456.该蛋白产品又称pkcb2, pkcbII, pkc b2, pkc bII, pkcbeta2, pkc beta2, pkc betaII, pkc beta2, Active PKC bII, PKC bII, human PKC BII, human PKC, human PKC beta-II, human PKC b-II, active kinase, active kinases, PKC, recombinant Active PKC bII, recombinant Active PKC bII, recombinant Active PKC beta-II, kinase activity assay, protein kinase等.

来源宿主

提供的【PKCbII】PKC β2蛋白,有活性的产品的来源为Sf9昆虫细胞-杆状病毒中重组表达.

溶解建议

提供的PKC β2蛋白,有活性的 产品为液态形式溶解于储存液(50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% 甘油)中.

保存建议

在您收到艾美捷发出的【PKCbII】PKC β2蛋白,有活性的产品后，建议将其置于-80°C保存.

其他

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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