中文名称

【ERK1】ERK1蛋白，有活性的（5 ug）

英文名字

ERK1, Active

供应商

Biovision

产品货号

7741-5

产品报价

￥已停产

产品说明书

购买方式

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产品新闻

背景资料

ERK1 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs), which are activated in response to numerous growth factors and cytokines. Activation of ERK1 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK1 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. In vitro studies indicate that ERK1 phosphorylate both nuclear and cytoplasmic proteins. Activated ERK1 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP β). The consensus primary sequence for substrate phosphorylation by ERK1 has been identified as -Pro-Leu-Ser/Thr-Pro-. ERK1 has been implicated in the control of a broad spectrum of cellular events in many types of cells. In somatic cells, ERK1 activation seems to be triggered after exit from a quiescent state (in G0 or G2) only and then inactivated by entry into a proliferative state.

序列

ERK1蛋白,有活性的蛋白产品，又称ERK, Mitogen-activated protein kinase 3 , Extracellular signal-regulated kinase 7, Extracellular signal-regulated kinase 8.其对应NCBI基因号为814，NCBI基因别称为CAMK4源，对应Accession号为Q16566.该蛋白产品又称erk-1, erk 1, Active ERK1, ERK1, ERK, human ERK1, active kinase, active kinases, recombinant ERK1, recombinant ERK, kinase activity assay, protein kinase等.

来源宿主

提供的【ERK1】ERK1蛋白,有活性的产品的来源为Sf9昆虫细胞-杆状病毒中重组表达.

溶解建议

提供的ERK1蛋白,有活性的 产品为液态形式溶解于储存液(50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% 甘油)中.

保存建议

在您收到艾美捷发出的【ERK1】ERK1蛋白,有活性的产品后，建议将其置于-80°C保存.

其他

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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