DDR2 is a member of a novel subclass of RTKs containing a distinct extracellular region encompassing a factor VIII-like domain (1) and is thought to be involved in the regulation of cell growth, differentiation, and metabolism. DDR2 plays a role in the regulation of collagen turnover mediated by smooth muscle cells in obstructive diseases of blood vessels and the lung (2).
序列
DDR2蛋白,有活性的蛋白产品,又称DDR, discoidin domain receptor tyrosine kinase 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10.其对应NCBI基因号为4915,NCBI基因别称为TRKB/ NTRK2源,对应Accession号为NM_001018064.该蛋白产品又称Active DDR2, DDR2, DDR, human DDR2, active kinase, active kinases, recombinant DDR2, recombinant DDR, kinase activity assay, protein kinase等.
来源宿主
提供的【DDR2】DDR2蛋白,有活性的产品的来源为Sf9昆虫细胞-杆状病毒中重组表达.
溶解建议
提供的DDR2蛋白,有活性的 产品为液态形式溶解于储存液(50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% 甘油)中.