PKCγ is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. In the brain, PKC is translocated to cell membranes during ischemia and is rapidly removed or degraded during the second otherwise lethal ischemic insult in preconditioned brains. This suggest that ischemic preconditioning enhances downregulation of cell signaling mediated by PKC and may thereby provide neuroprotection (1).
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PKC gamma蛋白,有活性的蛋白产品,又称PKC, protein kinase C, gammaprotein kinase C.其对应NCBI基因号为5600,NCBI基因别称为MAPK11源,对应Accession号为NM_002751.该蛋白产品又称Active PKC γ, PKC γ, PKC, PKC, human PKC γ, active kinase, active kinases, recombinant PKC γ, recombinant PKC, kinase activity assay, protein kinase等.