RSK3 is a member of the RSK (ribosomal S6 kinase) family that encodes a 733-amino-acid protein with a unique N-terminal region containing a putative nuclear localization signal (1). RSK3 mRNA is widely expressed and is activated by growth factors, serum and phorbol ester. Upon stimulation, RSK3 translocates to the cell nucleus and phosphorylates nuclear proteins. RSK3 can bind to ERK1/2 and this association increases the duration of RSK3 activation (2).
序列
RSK3蛋白,有活性的蛋白产品,又称RSK, ribosomal protein S6 kinase, 90kDa, polypeptide 2.其对应NCBI基因号为9578,NCBI基因别称为CDC42源,对应Accession号为NM_006035.该蛋白产品又称RSK-3, RSK 3, Active RSK3, RSK3, RSK, human RSK3, active kinase, active kinases, recombinant RSK, recombinant RSK3, kinase activity assay, protein kinase等.
来源宿主
提供的【RSK3】RSK3蛋白,有活性的产品的来源为Sf9昆虫细胞-杆状病毒中重组表达.
溶解建议
提供的RSK3蛋白,有活性的 产品为液态形式溶解于储存液(50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% 甘油)中.