CD antigen CD68 is also known as Macrosialin, Gp110, which belongs to the LAMP family. CD68 / Macrosialin is highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 / Macrosialin could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 / Macrosialin binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
序列
人源细胞表达 Fc TagCD68 / SR-D1 Protein又称CD68, Macrosialin, Gp110, SCARD1, LAMP4.其对应NCBI基因号为968,对应Accession号为P34810.
来源宿主
提供的【CD68】人源细胞表达 Fc TagCD68 / SR-D1 Protein蛋白产品来源为人胚肾HEK 293细胞中重组表达.
溶解建议
提供的人源细胞表达 Fc TagCD68 / SR-D1 Protein产品为固体冻干粉形式.推荐使用去离子水溶解,储存浓度为400 ug/mL. 室温下溶解30-60分钟,期间轻轻混匀.长期保存和进一步稀释的时候,推荐添加载体蛋白(0.1% (W/V) HSA or BSA).
保存建议
艾美捷推荐冰袋运输【CD68】人源细胞表达 Fc TagCD68 / SR-D1 Protein产品.我们建议您收到该产品后将其置于+4°C保存.产品有效期为收到产品后12个月.