A2B腺苷受体（胞外）抗体（25 ul）-Anti-A2B Adenosine Receptor （extracellular)代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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背景资料: Adenosine is an endogenous nucleoside generated locally in tissues under conditions of hypoxia, ischemia, or inflammation. It modulates a variety of physiological functions of many tissues including brain and heart. Adenosine exerts its action via four specific adenosine receptors (also named P1 purinergic receptors): A1-Adenosine Receptor (A1AR), A2A-Adenosine Receptor (A2AAR), A2B-Adenosine Receptor (A2BAR), and A3-Adenosine Receptor (A3AR). All are integral membrane proteins and are members of the G protein-coupled receptor superfamily, which share a common structure of seven putative transmembrane domains, an extracellular NH2 terminus, cytoplasmic COOH terminus, and a third intracellular loop important for binding G proteins. The adenosine receptors can be distinguished on the basis of their differential selectivity for adenosine analogs.

免疫原: A2B Adenosine 受体 (胞外)抗体的免疫原肽段为KDSATNN*STEPWDGTTNESC。此免疫原序列来源于147-166位氨基酸残基，该序列来源于人类A2B Adenosine 受体，替代 cysteine 154 (C154) with serine (*S) (Accession编号为P29275)，第二胞外环。

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