Alpha1A-肾上腺素受体（胞外）抗体（50 ul）-Anti-Alpha1A-Adrenoceptor （extracellular)代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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背景资料: Adrenoceptors (also called Adrenergic receptors) are the receptors for the catecholamines adrenaline and noradrenaline (called epinephrine and norepinephrine in the United States). Adrenaline and noradrenaline play important roles in the control of blood pressure, myocardial contractile rate and force, airway reactivity, and a variety of metabolic and central nervous system functions.The Adrenoceptors are members of the G-protein-coupled receptor (GPCR) superfamily of membrane proteins. They share a common structure of seven putative transmembrane domains, an extracellular amino terminus, and a cytoplasmic carboxyl terminus.TheAdrenoceptors are divided into three types: α1, α2 and β adrenoceptors. Each type is further divided into at least three subtypes: α1A, α1B, α1D, α2A, α2B, α2C, β1, β2, β3. 1,2They are expressed in nearly all peripheral tissues and in the central nervous system.

免疫原: Alpha1A-Adrenoceptor (胞外)抗体的免疫原肽段为EDETI*SQINEEPG(C)。此免疫原序列来源于171-183位氨基酸残基，该序列来源于人类α1A adrenoceptor ，替代 cysteine 176 (C176) with serine (*S) (Accession编号为 P35348)，第二胞外环。

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