C3a过敏毒素受体（胞外）抗体（50 ul）-Anti-C3a Anaphylatoxin Receptor （extracellular)代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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背景资料: C3a binds to C3a receptor, a G-protein coupled receptor which couples to Gi upon activation. Like all other members of the superfamily, C3a receptor has seven transmembrane domains with an extracellular N-terminus and intracellular C-terminal tail. The receptor has two glycosylation sites, an unusually large extracellular loop with a sulfated tyrosine residue important for ligand recognition and binding.C3a receptor is expressed in cells of myeloid origin like neutrophils, macrophages and dendritic cells to name a few. It is also detected in astrocytes from inflamed brain, endothelial cells and activated human T cells. mRNA of C3a receptor is detected in lung, liver, kidney, brain heart, muscle and testis.

免疫原: C3a Anaphylatoxin 受体 (胞外)抗体的免疫原肽段为(C)EDHETSPLDNSD。此免疫原序列来源于276-287位氨基酸残基，该序列来源于人类C3a anaphylatoxin 受体 (Accession编号为Q16581 )，第二胞外环。

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