Adenylyl Cyclase type 3 (AC3) is widely expressed in the olfactory tissue, human cell line HEK-293, bovine brain, spinal cord, adrenal medulla, adrenal cortex, heart atrium, aorta, lung and retina.Several studies have suggested that AC3 may play an important role in the regulation of glucose metabolism and body weight. It was found that overexpression of AC3 mRNA is involved in pathophysiological metabolic processes, such as type 2 diabetes. In addition, a recent study demonstrated the association of AC3 with gastric cancer as well as its tumorigenic potentials.Furthermore, AC3-knockout mice showed peripheral and behavioral anosmia.
应用类型
经验证,该抗体可应用于IC、IH、LCI、WB等实验应用,也可用于IFC、IP等实验。
免疫原
Adenylate Cyclase Type III (胞外)抗体的免疫原肽段为(C)KHVADEMLKDMKKDE。此免疫原序列来源于285-299 位氨基酸残基,该序列来源于大鼠Adenylate cyclase type III (Accession编号为P21932),第3胞外环。
来源宿主
兔
反应性
反应性:人、 小鼠、 大鼠
保存建议
艾美捷为您提供的Adenylate Cyclase Type III (胞外)抗体(50 ul)为室温运输,建议您收到产品后﹣20℃保存。