CaV2.1抗体抗体（25 ul）-Anti-CaV2.1 antibody代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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背景资料: Voltage dependent Ca2+ channels (Cav channels) are pivotal players in many physiological roles such as secretion, contraction migration and excitation.The voltage dependent calcium channels are composed of several subunits; α1, β, α2δ and γ. Cav channels were originally divided into six physiological types: L, N , P, Q, R, and T type.The Cav2.1 (formally named α1A) makes up the α1 poreforming subunit in P/Q type Ca2+ channel family. It is expressed preferentially in the central nervous system where along with Cav2.2 is responsible for pre-synaptic Ca2+ influx and neurotransmitter release.Mutations in the Cav2.1 have been shown to cause several neurological disorders among them are familial hemiplegic migraine, episodic ataxia type 2, and spinocerebellar ataxia type 6 (SCA6).

免疫原: CaV2.1 antibody抗体的免疫原肽段为(C)PSSPERAPGREGPYGRE。此免疫原序列来源于865-881 位氨基酸残基，该序列来源于大鼠CaV2。1 (Accession编号为P54282)。胞内环位于结构域 II和III。

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