TRPV2（胞外）抗体（25 ul）-Anti-TRPV2 （extracellular)代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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中文名称: TRPV2（胞外）抗体（25 ul）

英文名字: Anti-TRPV2 （extracellular)

供应商: Alomone

产品货号: ALO-ACC-039-25

产品报价: ￥已停产

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产品新闻

背景资料: TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells.1 The TRP channels have putative six-transmembrane domains (TM) with a pore domain between the fifth and the sixth TM, and all assemble as tetramers. Both the N- and the C-terminus of all TRPs are intracellular.According to IUPHAR, the TRP family is comprised of three main subfamilies on the basis of sequence homology; TRPC, TRPM and TRPV (to date, three additional subfamilies are also considered to belong to the TRP family: the TRPA, TRPML, and TRPP).The TRPV subfamily consists of six members, TRPV1-6.Four members of the TRPV family have been described as a thermosensitive ion channels (TRPV1 to TRPV4). Each channel exhibits distinct thermal activation thresholds ranging from noxious cold (<17°C) to noxious heat (>52°C). Although it shares around 50% homology with TRPV1, TRPV2 is not activated by capsaicin nor by protons. It has a high temperature threshold of ~52°C and is considered to play an essential role in the perception of high-intensity noxious heat stimulation. The TRPV2 is also considered to be a stretch-activated channel and to play a role in skeletal and cardiac muscle degeneration and pain pathway.8 TRPV2 channel is expressed in DRG neurons, different brain region and non-neuronal tissues such as spleen, lung and, intestine and in component of the immune system.

应用类型: 经验证，该抗体可应用于IC、IFC、IH、IP、LCI、WB等实验。

免疫原: TRPV2 (胞外)抗体的免疫原肽段为(C)HQPSLDQPAIPSSKAT。此免疫原序列来源于413-428 位氨基酸残基，该序列来源于大鼠TRPV2 (Accession编号为Q9WUD2)。第一胞外环。

来源宿主: 兔

反应性: 反应性：小鼠、大鼠

保存建议: 艾美捷为您提供的TRPV2 (胞外)抗体(25 ul)为室温运输，建议您收到产品后﹣20℃保存。

其他: Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证，以冻干粉形式提供，可确保产品生物活性和保质期。Alomone可提供多种包装规格，灵活方便。作为Alomone Labs在中国的区域总代理，开云·官方站线上登录平台入口_开云(中国) 将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。