CaVAlpha2Delta4（胞外）-ATTO-594抗体（50 ul）-Anti-CaVAlpha2Delta4 （extracellular)-ATTO-594代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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背景资料: The α2δ subunit regulates many functional aspects of Ca2+ channels, such as gating, regulating voltage dependent kinetics, and increasing functional channel density on the plasma membrane5. There are four proteins that comprise CaVα2δ: CaVα2δ1, CaVα2δ2, CaVα2δ3 and CaVα2δ46. CaVα2δ4 participates in the regulation of membrane expression of CaV channels. It is predominantly expressed in certain types of endocrine cells. It is also detected in the erythroblasts in the fetal liver, in the cells of the zona reticularis of the adrenal gland and in the basophiles of the pituitary7. Defects in CaVα2δ4 are the cause of retinal cone dystrophy 4 (RCD4). RCD4 is characterized by minimal symptoms except for slowly progressive reduction in visual acuity. ATTO dyes are characterized by strong absorption (high extinction coefficient), high fluorescence quantum yield, and high photo-stability. The ATTO-594 fluorescent label belongs to the class of Rhodamine dyes and can be used with fluorescent equipment typically optimized to detect Texas Red and Alexa-594.

免疫原: CaVAlpha2Delta4 (胞外)-ATTO-594抗体的免疫原肽段为(C)SERPQEMGRLLGEADG。此免疫原序列来源于881-896 位氨基酸残基，该序列来源于小鼠 Cavα2δ4 (Accession编号为Q5RJF7)。胞外。

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