CaVBeta2抗体（25 ul）-Anti-CaVBeta2代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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一抗

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背景资料: On the basis of their voltage activation properties, voltage-gated Ca2+ subtypes can be further divided into two broad groups: the low (T-type) and high (L, N, P, Q and R-type) threshold-activated channels2. The activity of the channel pore is modulated by 4 tightly-coupled subunits: an intracellular β subunit; a transmembrane γ subunit; and a disulphide-linked complex of α2 and δ subunits. There are four distinct β subunits: β1, β2, β3 and β4. There are 4 splice variants of the β2 subunit: β2a, β2b, β2c and β2d. β2a and β2b are expressed in heart, aorta and brain, and are 606- and 632-residue proteins, respectively. β2c and β2d (655 and 604 residues, respectively) are expressed in brain, and recent studies show beta-2c to be also expressed in heart. All splice variants differ in their N-terminal regions.

免疫原: CaVBeta2抗体的免疫原肽段为(C)HEHVDRYVPHREHNHRE。此免疫原序列来源于571-587 位氨基酸残基，该序列来源于大鼠Cavβ2 (Accession编号为Q8VGC3)。胞内, C端。

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