CaVGamma5（胞外）抗体（25 ul）-Anti-CaVGamma5 （extracellular)代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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背景资料: CaVγ subunits inhibit CaV channel activity and modulate its activation and inactivation kinetics. CaVγ subunits have little effect on CaV channel trafficking. The γ subunit is an integral membrane protein. The γ subunit family consists of at least 8 members, which share a number of common structural features. Each member is predicted to possess four transmembrane domains, with intracellular N- and C-termini. The first extracellular loop contains a highly conserved N-glycosylation site and a pair of conserved cysteine residues.n The CaVγ5 subunit is highly expressed in the liver, kidney, heart, lung, skeletal muscles, and, with a lower abundance, in testes. The close association of epilepsy and ataxia with mutations in other neuronal voltage-dependent Ca2+ channels suggests these are potential candidate phenotypes for defects in the CaVγ5 (CACNG5) gene.

免疫原: CaVGamma5 (胞外)抗体的免疫原肽段为(C)SESTVNVLKMIRS。此免疫原序列来源于87-99 位氨基酸残基，该序列来源于大鼠Cavγ5 (Accession编号为Q8VHW8)，第二胞外环。

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