D3多巴胺受体（胞外）抗体（25 ul）-Anti-D3 Dopamine Receptor （extracellular)代理/参数/厂家-一抗-开云·官方站线上登录平台入口

PRODUCT CENTER

一抗

开云·官方站线上登录平台入口_开云(中国)

当前位置：开云·官方站线上登录平台入口 > 开云·官方站线上登录平台入口_开云(中国) > 免疫学产品 > 一抗

中文名称: D3多巴胺受体（胞外）抗体（25 ul）

英文名字: Anti-D3 Dopamine Receptor （extracellular)

供应商: Alomone

产品货号: ALO-ADR-003-25

产品报价: ￥已停产

产品说明书

购买方式: 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868。

产品新闻

背景资料: The D3 Dopamine Receptor (D3 receptor) is one of five receptors that mediate the effects of the catecholamine neurotransmitter dopamine. Dopamine regulates a variety of functions including locomotor activity, emotion, positive reinforcement, food intake, and endocrine regulation. The dopaminergic system has been extensively studied in the last thirty years mainly because its dysregulation has been linked to several neurological and neuropsychiatric diseases including Parkinson’s disease and schizophrenia.nAll five dopamine receptors belong to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily.nHistorically, the five receptors have been divided into two subfamilies based on pharmacological and structural considerations: the D1-like subfamily (that includes the D1 and D5 subtypes) and the D2-like subfamily (that includes the D2-, D3- and D4 subtypes).nThe D1-like receptors are coupled to Gs-type G proteins and enhance adenylate cyclase activity while the D2-like receptors are coupled to Gi-type G proteins and inhibit adenylate cyclase activity.nThe D3 receptor distribution in the brain is relatively restricted to limbic areas such as striatum, islands of Calleja and olfactory tubercle. In the periphery, it is expressed in the kidney particularly in proximal tubules.nThe exact physiological function of the D3 receptor remains to be fully elucidated. In studies using D3 receptor knockout mice, the most prominent dysfunction was the development of rennin-dependent hypertension. Potential roles in reinforcement and reward behaviors have also been suggested as well as roles in neuropsychiatric disorders such as drug abuse and schizophrenia.

应用类型: 经验证，该抗体可应用于IH、WB等实验。

免疫原: D3 Dopamine 受体 (胞外)抗体的免疫原肽段为CGAENSTGVNRARPH。此免疫原序列来源于15-29 位氨基酸残基，该序列来源于大鼠D3 Dopamine 受体 (Accession编号为P19020)。胞外，N端。

来源宿主: 兔

反应性: 反应性：小鼠、大鼠

保存建议: 艾美捷为您提供的D3 Dopamine 受体 (胞外)抗体(25 ul)为室温运输，建议您收到产品后﹣20℃保存。

其他: Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证，以冻干粉形式提供，可确保产品生物活性和保质期。Alomone可提供多种包装规格，灵活方便。作为Alomone Labs在中国的区域总代理，开云·官方站线上登录平台入口_开云(中国) 将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。