兴奋性氨基酸转运蛋白2（胞外）-ATTO-633抗体（50 ul）-Anti-Excitatory Amino Acid Transporter 2 （extracellular)-ATTO-633代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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背景资料: EAAT2 (also known as Glutamate Transporter-1, GLT-1) as well as EAAT1, is expressed predominantly in glia cells, while EAAT3, EAAT4 and EAAT5 are mostly expressed in neurons.nAs mentioned earlier, EAAT transporters represent the only (significant) mechanism for removal of glutamate from the extracellular fluid and hence are essential for the long-term maintenance of low and non-toxic concentrations of glutamate and the preservation of normal excitatory synaptic transmission.nIn addition to Glu uptake, the glutamate transporters provide glutamate for the synthesis of γ-Aminobutyric acid (GABA), glutathione and protein, suggesting an interactive role between EAATs and cellular metabolism.nDysregulation of EAAT activities has been implicated in several neurodegenerative disorders such as Alzheimer’s disease, traumatic brain injury, epilepsy and schizophrenia, suggesting that EAATs can be a useful target for the treatment of these conditions.

免疫原: Excitatory Amino Acid Transporter 2 (胞外)-ATTO-633抗体的免疫原肽段为(C)KQLGPGKKNDEVS。此免疫原序列来源于151-163 位氨基酸残基，该序列来源于大鼠EAAT2。 (Accession编号为P31596)，第二胞外环。

保存建议: 艾美捷为您提供的Excitatory Amino Acid Transporter 2 (胞外)-ATTO-633抗体(50 ul)为室温运输，建议您收到产品后﹣20℃保存。

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