甘丙肽受体2型抗体（50 ul）-Anti-Galanin Receptor Type 2代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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背景资料: Galanin is a neuropeptide, consisting of 29-30 amino acid residues, involved in the regulation of cognition, mood, feeding, seizure activity and pain. Galanin exerts its action via three known Galanin Receptors, the Galanin Receptor Type 1 (GALR1), Galanin Receptor Type 2 (GALR2) and Galanin Receptor Type 3 (GALR3). The Galanin Receptors belong to the G-Protein Coupled Receptor superfamily.nGALR2 is widely expressed in the brain (with highest levels of mRNA found in the hypothalamus, hippocampus, amygdala and pyriform cortex) and in peripheral tissues such as the small intestine, heart, kidney, and liver. GALR2 high levels of expression were also found in rat dorsal root ganglia.GALR2 activation increases inositol phosphate hydrolysis, mediates the release of Ca2+ into the cytoplasm from intracellular stores, and opens Ca2+-dependent chloride channels in a PTX-resistant manner, indicating that GALR2 couples to Gq/11 proteins.

免疫原: Galanin 受体 Type 2抗体的免疫原肽段为肽段：(C)GSGSQRAKRKVTR。此免疫原序列来源于223-235 位氨基酸残基，该序列来源于小鼠 Galanin 受体 type 2 (Accession编号为O88854)。第三胞内环。

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