Melatonin (N-acetyl-5-methoxytryptamine) is a product of tryptophan metabolism. It is synthesized in the pineal gland and is secreted to control the circadian rhythm. Melatonin is also synthesized in the gastrointestinal tract, retina, skin and other tissues where it acts in a autocrine or paracrine manner. The role of melatonin in these tissues is independent of its role in the circadian rhythm, where it plays a role in energy metabolism, physiological growth, differentiation and responsiveness in stress stimuli. The pleiotropic effects of melatonin have given rise to various therapeutic possibilities for this molecule. For example; anti-stress, sexual dysfunction, obesity, gallbladder stones. To date, the only therapeutic uses for melatonin remain to treat sleep disorders, depression, migraine and headaches
应用类型
经验证,该抗体可应用于IH、WB等实验应用,也可用于IFC、IP等实验。
免疫原
Melatonin 受体 type 2抗体的免疫原肽段为(C)RKAKATRKLRLRPSD。此免疫原序列来源于232-246 位氨基酸残基,该序列来源于小鼠 Melatonin 受体 Type 2 (Accession编号为Q8CIQ6)。 第三胞内环。
来源宿主
兔
反应性
反应性:小鼠、 大鼠
保存建议
艾美捷为您提供的Melatonin 受体 type 2抗体(25 ul)为室温运输,建议您收到产品后﹣20℃保存。