KV7.4抗体（25 ul）-Anti-KV7.4代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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一抗

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背景资料: The KCNQ (KV7) family of channels consists of five members (KV7.1, KV7.2, KV7.3, KV7.4 and KV7.5). KCNQ channels commonly display activation at voltages close to neuronal resting membrane potentials and are regulated by G-protein coupled receptor (GPCR) signaling, notably by muscarinic receptors.nThe KCNQ4 (KV7.4) encodes a protein of 695 amino acid residues. The homology with other members of the KCNQ family ranges from 37 to 44% at the amino acid level. KCNQ4 protein contains six domains that span the plasma membrane, and a P-loop domain which forms the K+-selective channel pore. The fourth transmembrane domain contains the voltage sensor, which is responsible for the electrically driven conformational change that leads to channel opening. Functional channels are formed by a tetrameric assembly of KCNQ4 subunits, typically in homotetrameric form, but heterotetrameric co-assembly of different members is allowed

免疫原: KV7.4抗体的免疫原肽段为(C)DRKTREKGDKGPSD。此免疫原序列来源于594- 607 位氨基酸残基，该序列来源于小鼠 KV7。4 (Accession编号为Q9JK97)。胞内, C端。

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