Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues. In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain, it acts as a neurotransmitter in both a stimulatory and an inhibitory manner.Somatostatin mediates its action via six high affinity G-protein-coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4, and SSTR5), which are encoded by five genes.Expression of the different receptors is developmentally regulated in a time- and tissue-specific manner.In general, SSTR2 is the most common SSTR subtype found in human tumors, followed by SSTR1, with SSTR3 and SSTR4 being less common.
应用类型
经验证,该抗体可应用于IC、IH、LCI、WB等实验应用,也可用于IFC、IP等实验。
免疫原
Somatostatin 受体 Type 2 (胞外)抗体的免疫原肽段为(C)GSNQTEPYYDMTSN。此免疫原序列来源于30-43 位氨基酸残基,该序列来源于大鼠SSTR2 (Accession编号为 P30680)。胞外,N端。
来源宿主
兔
反应性
反应性:人、 小鼠、 大鼠
保存建议
艾美捷为您提供的Somatostatin 受体 Type 2 (胞外)抗体(50 ul)为室温运输,建议您收到产品后﹣20℃保存。