Sphingosine 1-Phosphate受体2抗体（25 ul）-Anti-Sphingosine 1-Phosphate Receptor 2代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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背景资料: Lysophospholipids constitute a group of important lipid mediators; lysophosphatidic acid (LPA) a glycerolysophospholipid and sphingosine 1-phosphate (SIP), a lysosphingolipid. Sphingosine 1-phosphate is a bioactive lipid derived from metabolism of sphingomyelin. Sphingosine 1-phosphate is implicated in the regulation of many cellular functions including proliferation, apoptosis, survival, adhesion, differentiation, and migration.nSphingosine 1-phosphate exerts its activity through five distinct G-protein-coupled receptors, (also named endothelial differentiation gene receptors - EDG); S1PR1 (EDG-1), S1PR2 (EDG-5), S1PR3 (EDG-3), S1PR4 (EDG-6), and S1PR5 (EDG-8).nSphingosine 1-Phosphate Receptor 2 (S1PR2) is ubiquitously expressed. S1PR2 mRNA was detected in the brain, heart, spleen, liver, lung, thymus, kidney and skeletal muscle4. Unlike S1PR1, knockout of SIPR2 gene is not lethal

免疫原: Sphingosine 1-Phosphate 受体 2抗体的免疫原肽段为ERQVALAKVKLYGSDKSC。此免疫原序列来源于129-146 位氨基酸残基，该序列来源于小鼠 Sphingosine 1-Phosphate 受体 2 (S1PR2), (Accession编号为P52592)。第二胞内环。

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