(-)-Cytisine is an alkaloid, which is occurring naturally in several types of plants as well as in animals feeding on them (see an example in reference #1). (-)-Cytisine is a potent and selective agonist of neuronal nAChR. It acts as a partial agonist at β2-containing nAChR.
产品描述
A nAChR Agonist and a Partial Agonist of beta2 Subunit
产品形式
(-)-Cytisine is an alkaloid, which is occurring naturally in several types of plants as well as in animals feeding on them (see an example in reference #1). (-)-Cytisine is a potent and selective agonist of neuronal nAChR. It acts as a partial agonist at β2-containing nAChR.nEC50s differ for different subunits composed channels; for recombinant human channels expressed in Xenopus oocytes the following EC50 values were reported: 25 µM, 39 µM, 67 µM, 72 µM, 2.6 µM 0.9 µM and 71 µM for α2/β2, α2/β4, α3/β2, α3/β4, α4/β2, α4/β4 and α7 respectively.