中文名称

1,1-二甲基-4-苯基哌嗪碘化物（5克）

英文名字

1,1-Dimethyl-4-phenylpiperazinium iodide

供应商

Alomone

产品货号

ALO-D-125-5

产品报价

￥已停产

产品说明书

购买方式

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产品新闻

背景资料

1,1-Dimethyl-4-phenylpiperazinium iodide (DMPP) is a selective nAChR agonist. For a long time, DMPP was considered to be the prototype of ganglionic stimulating agents, since it was able to activate the nicotinic receptor in sympathetic ganglia with higher potency than the muscle-type. However, it has since been shown that DMPP binds with higher affinity to the nicotinic receptor in the brain. 1,1-Dimethyl-4-phenylpiperazinium iodide activates had IC50 of 0.77 uM on α4 nicotinic channel expressed in xenopus oocytes.

产品描述

An Agonist of nAChR

产品形式

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels comprising five subunits. The muscle-type receptor is made of two α1 β, γ and δ subunits, while the neuronal nicotinic receptors are formed by different combination of 2 α and 3 β subunits. These receptors are expressed on neuronal and different types of non-neuronal cells like: lymphocytes, alveolar macrophages, airway smooth muscle cells, epithelial cells, and fibroblasts.nnAChRs mediate numerous specific physiological functions depending on the type of cell involved. For example, nicotine induces the release of dopamine in the central nervous system and stimulates nitric oxide (NO) synthase gene expression in endothelial cells.

保存建议

艾美捷为您提供的Alonmone Labs原装进口的1,1-Dimethyl-4-phenylpiperazinium iodide (5 g)产品可室温运输，建议您在收到产品后将其置于合适的温度下保存。

其他

Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证，以冻干粉形式提供，可确保产品生物活性和保质期。Alomone可提供多种包装规格，灵活方便。作为Alomone Labs在中国的区域总代理，开云·官方站线上登录平台入口_开云(中国) 将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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