Hemitoxin is a 35 amino acid peptidyl toxin isolated from the Hemiscorpius lepturus scorpion venom and belongs to the αKTx6 family. It reversibly blocks Kv1.1, Kv1.2 and Kv1.3 voltage-gated K+ channels with an IC50 of 13 nM, 16 nM and 2 nM, respectively1. It shares 80% sequence similarity with Maurotoxin, and has a unique pairing of its four disulfide bridges.
产品描述
A Potent Blocker of KV1.1, KV1.2 and KV1.3 K+ Channels
产品形式
Hemitoxin is a 35 amino acid peptidyl toxin isolated from the Hemiscorpius lepturus scorpion venom and belongs to the αKTx6 family. It reversibly blocks Kv1.1, Kv1.2 and Kv1.3 voltage-gated K+ channels with an IC50 of 13 nM, 16 nM and 2 nM, respectively1. It shares 80% sequence similarity with Maurotoxin, and has a unique pairing of its four disulfide bridges.