【CRABP1】小鼠抗人细胞维甲酸结合蛋白1抗体-Mouse Anti Human Cellular Retinoic Acid binding Protein 1代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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一抗

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背景资料: CRABP1 is a member of special carrier proteins for members of the vitamin A family. It is believed that CRABP1 has an essential role in retinoic acid-mediated differentiation and proliferation processes. Though， CRABP1 is structurally similar to the cellular retinol-binding proteins， it binds only retinoic acid at specific sites within the nucleus， which may contribute to vitamin A-directed differentiation in epithelial tissue. CRABP1 is constitutively expressed and is thought to have different functions in the cell than the related CRABP2. CRABP1 forms a beta-barrel structure which accommodates hydrophobic ligands in its interior. Loss of CRABP1 function as a result of hypermethylation of its promoter leads to pathogenesis of papillary thyroid carcinoma. Furthermore， frequent methylation-associated silencing of CRABP1 is linked to esophageal squamous-cell carcinoma.

免疫原: Anti-human CRABP1 mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CRABP1 amino acids 1-137 purified from E. coli.

保存建议: 建议在您收到小鼠抗人细胞维甲酸结合蛋白1抗体产品后，按照如下建议进行保存：4℃大约保存1个月，长期保存，推荐保存于-20℃。请避免反复冻融。

其他: ProSpec 是一家全球著名细胞因子蛋白生产和研发的公司，具有20多年的生产经验，专注于蛋白（重组及合成）生产研发。我们的核心产品包括：干扰素、白介素、骨蛋白、肿瘤坏死因子、成纤维生长因子、瘦素、干细胞因子、催乳素、表皮生长因子、胰岛素样生长因子、神经生长因子、集落刺激因子、激素、酶、病毒抗原以及各种重组蛋白等。n领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。