Mouse Anti Human CASP8 and FADD-like apoptosis regulator
供应商
Prospec
产品货号
ANT-433
产品报价
¥询价/100ug ¥20ug ¥5ug
产品说明书
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产品新闻
背景资料
CFLAR contains two death effector domains (DEDs) and a caspase-like domain. CFLAR may play a critical role between cell survival and cell death pathway in mammalian cells. CFLAR also interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (death receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (tumor necrosis factor receptor 1).
应用类型
ELISA, Western blot
免疫原
Anti-human CFLAR mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CFLAR amino acids 1-376 purified from E. coli.