Phospho-FGFR1 (Tyr654) polyclonal antibody-Phospho-FGFR1 (Tyr654) polyclonal antibody代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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背景资料: Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through cell surface receptor tyrosine kinases. Each receptor contains an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. Seven tyrosine residues in the cytoplasmic tail of FGFR1 can be phosphorylated: Tyr463, 583, 585, 653, 654, 730, and 766.

免疫原: The antiserum was produced against synthesized peptide derived from human FGFR1 around the phosphorylation site of Tyr654. AA range:626-675

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