Phospho-Cardiac Troponin I (Ser22/Ser23) polyclonal antibody
英文名字
Phospho-Cardiac Troponin I (Ser22/Ser23) polyclonal antibody
供应商
Bioworld
产品货号
BZ16417
产品报价
¥询价/50ul
产品说明书
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产品新闻
背景资料
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
应用类型
WB,IHC-P,ELISA
免疫原
The antiserum was produced against synthesized peptide derived from rat TNNI3 around the phosphorylation site of Ser22 and Ser23. AA range:5-54