针对 HCV 亚型 1b NS5B 蛋白的部分人源化重组抗体-Partially humanized recombinant antibody to HCV subtype 1b NS5B protein代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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英文名字: Partially humanized recombinant antibody to HCV subtype 1b NS5B protein

背景资料: Non-structural protein 5B (NS5B) represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, which is a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronic hepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunit RNA-dependent RNA polymerase is absolutely essential for the viral replication.nnAntibody is derived from mouse anti-HCV NS5B monoclonal antoibody 9A2 expressing mouse hybridoma culture. cDNA of antibody variable regions were isolated and cloned into the human IgG1 constant region-containing antibody expression vector. Partially humanized, chimeric antibody was expressed by QMCF CHOEBNALT85 cell line. Antibody is used for high-specific efficient detection of soluble or membrane-bound proteins fused with 9A2 epitope-tag sequence.

反应性: Human, HCV subtype 1b NS5B, Epitope mapped to amino acids 111-130 (LSSKAVNHIRSVWKDLLEDT)

保存建议: Store at - 20 …-70 °C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles as product degradation may result.

其他: Icosagen AS成立于1999年，总部位于爱沙尼亚，提供一系列现成产品，如抗体、蛋白质、ELISA试剂盒等，以及天然橡胶过敏原检测和食品质量控制领域的质量控制服务。产品涵盖的应用领域有：神经生物学，病毒学，心脏标志物，细胞因子，炎症，过敏原等。Icosagen提供用于诊断和研究的重组抗体和抗原。Icosagen将现代重组技术和20年的制药经验引入诊断领域，以开发和生产高质量的试剂。利用Icosagen的专利系列，开发和生产高亲和力和特异性的单克隆和多克隆抗体。Icosagen已通过ISO 9001:2015认证，并遵循GLP指南。