Recombinant Human N-acetylneuraminic acid synthase
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ProSpec
产品货号
ENZ-024
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¥询价/1mg ¥20ug ¥5ug
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背景资料
NANS is a 359 amino acid protein that contains one AFP(antifreeze proteins)-like domain and functions in the biosynthesis of sialic acids. The ubiquitously expressed NANS enzymatically catalyzes the H2O-dependent formation of N-acetylneuraminic acid(Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid(KDN), both of which are sialic acids. NANS uses N-acetylmannosamine 6-phosphate as a substrate for Neu5Ac synthesis and mannose 6-phosphate as a substrate for KDN synthesis.