Recombinant Human Ubiquitin Conjugating Enzyme E2D1
供应商
ProSpec
产品货号
ENZ-116
产品报价
¥询价/1mg ¥20ug ¥5ug
产品说明书
购买方式
在线支付宝及网银支付、支票、现金、电汇,或拨打全国免费服务电话4006800868与我们联系.
产品新闻
背景资料
UBE2D1 is a member of the ubiquitin-conjugating enzyme family. Ubiquitination involves at least 3 classes of enzymes: ubiquitin-activating enzymes(E1s), ubiquitin-conjugating enzymes(E2s) and ubiquitin-protein ligases(E3s). UBE2D1 is strongly related to a stimulator of iron transport(SFT), and is up-regulated in hereditary hemochromatosis. In addition, UBE2D1 functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.