Recombinant Human NEDD8 Activating Enzyme E1 Subunit 1
供应商
ProSpec
产品货号
ENZ-227
产品报价
¥询价/10ug ¥1mg ¥2ug
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产品新闻
背景资料
NEDD8-activating enzyme E1 regulatory subunit(NAE1) is a member of the ubiquitin-activating E1 family. NAE1 binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is believed to have a role in the pathogenesis of Alzheimer’s disease. NAE1 participates in a unique ubiquitinylation-related pathway involving the ubiquitin-like molecule NEDD8. Furthermore, the NAE1 protein is essential for cell cycle progression through the S/M checkpoint.