Recombinant Human Ubiquitin-Conjugating Enzyme E2I , His tag
供应商
ProSpec
产品货号
ENZ-274
产品报价
¥询价/1mg ¥50ug
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产品新闻
背景资料
Human Ubquitin Conjugating Enzyme 9(Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumolyation, and may play a role in substrate recognition. Ubc9 can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, I?B?, and PML without the requirement of an E3 ligase.