Recombinant Human Ubiquitin-Like Modifier Activating Enzyme 5
供应商
ProSpec
产品货号
ENZ-602
产品报价
¥询价/10ug ¥1mg ¥2ug
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产品新闻
背景资料
Ubiquitin-like modifier activating enzyme 5(UBA5) is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme(E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates an ubiquitin-like protein, ubiquitin-fold modifier 1(Ufm1), by forming a high-energy thioester bond. UBA5 is located primarily in cytoplasm, while it generally localizes to the nucleus in presence of SUMO2.