Recombinant Human Uridine Monophosphate Synthetase
供应商
ProSpec
产品货号
ENZ-663
产品报价
¥询价/1mg ¥20ug ¥5ug
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产品新闻
背景资料
Uridine 5’-monophosphate synthase(UMPS), is a bifunctional enzyme that catalyzes the ultimate two steps of the de novo pyrimidine biosynthetic pathway. UMPS in eukaryotes links the orotate phosphoribosyltransferase and the orotidine-5’-monophosphate(OMP) decarboxylase activities into a single protein. The harmony of these 2 enzymes is assumed to be stabilized the catalytic centers as a result of the low molar concentration of the protein in mammalian cells.mutations in this gene are the reason of inherited orotic aciduria disease.