Recombinant Human DnaJ (Hsp40) Homolog, Subfamily B, Member 8
供应商
ProSpec
产品货号
HSP-050
产品报价
¥询价/1mg ¥25ug ¥5ug
产品说明书
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产品新闻
背景资料
DnaJ homolog subfamily B member 8 (DNAJB8) is superior suppressors of aggregation and toxicity of disease-associated polyglutamine proteins.DNAJB8 is a member of the DNAJ/HSP40 family of proteins that regulate chaperone activity. DNAJB8 is (de)acetylated at 2 conserved C-terminal lysines which aren’t involved in substrate binding, but do have a role in suppressing protein aggregation. DNAJB8 has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma.