鸟氨酸脱羧酶I（ODC1）抑制剂筛选试剂盒（比色）-Ornithine Decarboxylase I (ODC1) Inhibitor Screening Kit (Colorimetric)代理/参数/厂家-细胞分析试剂盒-开云·官方站线上登录平台入口

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细胞分析试剂盒

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英文名字: Ornithine Decarboxylase I (ODC1) Inhibitor Screening Kit (Colorimetric)

产品描述: Ornithine decarboxylase (ODC) (EC 3.5.3.1) is a pyridoxal phosphate-dependent enzyme, which cleaves ornithine into putrescine and carbon dioxide. ODC is the initial step in the polyamine synthesis pathway. Putrescine, along with the subsequent polyamine products, spermidine and spermine has been shown to promote cell proliferation and arrest cell apoptosis in cancer. It is also known that proto-oncogenes, such as c-Myc can transcriptionally regulate this protein. Ornithine decarboxylase inhibitors, e.g. efluornithine (2-difluromethylornithine), alexidine and their analogs have been studied as ornithine and employed to irreversibly inhibit ODC and thus abolish cell growth by reducing intracellular polyamine that is required for the aforementioned cellular process. BioVision’s Ornithine Decarboxylase I (ODC1) Inhibitor Screening Kit is designed for screening potential human ODC1 inhibitors. DFMO is provided as an inhibitor control. The ODC1 activity is monitored by the decrease in absorbance readings (OD: 340 nm), while potential inhibitors will cause a decrease in the rate of absorbance change. The assay kit is simple, quick and can be used to identify and characterize ODC1 inhibitors in a high-throughput format.

产品特点: Fast and convenient,Simple procedure; takes ~ 30-60 minutes,The assay ensures maximal sensitivity, consistent light output, as well as accuracy and consistency when working with multiple samples,Useful for screening possible inhibitors of human Ornithine decarboxylase I (ODC1)

其他: BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.