EZClick™TUNEL –原位DNA片段化/凋亡分析试剂盒

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细胞分析试剂盒

开云·官方站线上登录平台入口_开云(中国)

产品描述: Apoptosis is a controlled phenomenon in which apoptotic cells are characterized by changes in nucleus (i.e. chromatin condensation, DNA fragmentation), cytoplasm shrinkage and production of apoptotic bodies. These are subsequently phagocytosed by macrophages, parenchymal cells, or neoplastic cells. DNA strand breaks can be analyzed by TUNEL (Terminal deoxynucleotidyl transferase dUTP Nick End-Labeling) assays. BioVision’s EZClickTM TUNEL-DNA fragmentation/Apoptosis Assay utilizes modified EdUTP nucleotides which are incorporated at the 3’-OH ends of fragmented DNA by Terminal deoxynucleotidyl transferase (TdT) enzyme and detected based on a click reaction. This assay enables easy delivery and incorporation of EdUTP coupled with high selectivity of detection of DNA damage. The assay is performed under mild reaction conditions which preserve cell morphology, thus enabling the identification of damaged DNA by FACS or fluorescence microscopy. Our assay is fast and capable of detecting a higher percentage of apoptotic cells than the antibody based methods. The kit contains sufficient reagents to detect total/fragmented DNA in apoptotic cells in a 1 X 96-well plate or on 50 cover slips.

产品特点: Does not require antibodies, avoiding lengthy incubation times and does not require washes,Specific, sensitive,Compatible with Flow Cytometry and Fluorescence Microscopy instruments

其他: BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.