Caspase family consists of more than 10 members. Based on their extended substrate specificities, these enzymes were divided into three major groups: Group I (contains caspase-1,-4,-5), Group II (contains caspase-2,-3,-7), and Group III (contains caspase-6,-8,-9,-10). Evidences have suggested that Group I caspases are involved primarily in the production of inflammatory cytokines, while group II and III enzymes function in apoptosis as effectors and upstream activators, respectively. The Group III recombinant caspases were expressed in E. coli and routinely tested for their ability to enzymatically cleave the substrate VEID-pNA (for caspase-6), IETD-pNA (for caspase-8 & -10) and LEHD-pNA (for caspase-9), respectively.
序列
活性的人Caspase套装组III蛋白产品,又称待更新.其对应NCBI基因号为CASP2- 835
CASP3- 836
CASP7- 840
,NCBI基因别称为CASP2
CASP3
CASP7 ;该基因种属来源为人源,对应Accession号为CASP2- P42575
CASP3- P42574
CASP7- P55210.该蛋白产品又称Active Human Caspases group, active human caspase, active caspases, human caspases, caspase enzyme, caspase protein等.
来源宿主
提供的【Caspases Group III】活性的人Caspase套装组III产品的来源为大肠杆菌中重组表达.